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Sip water between meals, not during

2020;192(31):E875E891

However, to ensure maximum efficacy, we strongly advise refrigerating the vial as soon as you have the opportunity, and using an insulated bag and cold packs to help keep the medicine within the correct temperature range when refrigeration isnt available

Do not use medication past its beyond-use date

Although there are no standard criteria for the clinical and biomarker evidence required to support disease modification, clinical measures such as a change in trajectory of decline, an increasing drug versus placebo difference over time, an increased time to event, and an enduring change after discontinuation support this terminology