(Sidenote: The skins ability to absorb chemicals is why its so important to critically examine your personal skin care products and why we recommend switching to safer shampoos, body washes, household cleaners and laundry detergents) Studies have shown topical application of glutathione raises glutathione levels, and we have tested this ourselves
For your skin, you have to see the long-term investment
Proc Natl Acad Sci USA (2021) 118:111
3.1.3 Phospholipid oxidation products and inflammatory signaling Oxidized phospholipids generated through peroxidation, such as hydroxylated lipids and keto-lipids, not only compromise the integrity of the cell membrane directly but also increase membrane tension in tandem with enhanced lipid peroxidation
That said: Long-term use should be structured, not random Periodic breaks or reassessment are sensible Quality of formulation matters more than duration Clinically formulated products like Glutone 1000 are designed for sustained use without unnecessary overload