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Additionally, Safranin-O staining of the ankle joints revealed cartilage tissue destruction and severe synovial proliferation in the saline group

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While there is some limited evidence of the efficacy of 1,000 micrograms daily dosing of oral cyanocobalamin, this is mainly based on the correction of serum vitamin B12 levels, rather than any impact on clinical signs and symptoms[24]

The melanocyte differentiation program predisposes to metastasis after neoplastic transformation

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