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Approaches such as intrathecal, intracerebroventricular, and intraparenchymal injections, as well as transient BBB disruption, have been employed to deliver drugs with limited CNS bioavailability (Rezaee et al., 2025)

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If a product appears on the FDA database with a valid FR# (Food Registration Number) and compliant labeling, it is considered safe and legally allowed for sale

10.1016/j.biocel.2006.07.001 Int J Biochem Cell Biol