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Furthermore, data showing whether 'responders' had lower baseline concentrations of GSH or GSH:GSSG were not provided

Since the liver is the "factory" for glutathione, keeping it healthy is key

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With toxicity, manganese-induced damage is found in the substantia nigra, globus pallidus, and caudate nucleus with depletion of dopamine and serotonin levels and has been linked to psychiatric changes followed by impaired motor activity with muscle rigidity and tremors