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Diarrhoea (defined as three or more loose or watery stools per day) is an uncommon side effect of vitamin B12 supplementation , though it is listed as a rare or uncommon adverse reaction in the official product information for both oral cyanocobalamin and injectable hydroxocobalamin preparations

Vitamin B12 deficiency is increasingly recognised as a global public health concern, particularly in developing countries and among high-risk populations

Signs of B12 deficiency: Oral B12 supplements require absorption through the gastrointestinal tract

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Usually 24 to 36 months , depending on storage conditions and packaging