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In recent years, electromotive drug administration (EMDA) as a new delivery approach was developed to increase the concentration of drugs into specific tissues (Mehrsai et al., 2013)
With the exception of FOSL1, which was undetectable in all of the samples in the ELISA test, the protein level regulation of IL-1, IL8, HSPA1A by the copper compounds were similar with the gene level regulation
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