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Blood sugar effects: The glucose-lowering properties that constitute MOTS-c's primary benefit could theoretically cause hypoglycemia in susceptible individuals, particularly those using diabetes medications

Abbreviations HF: Heart failure T2DM: Type 2 diabetes mellitus SGLT2is: Sodium-glucose cotransporter-2 inhibitors GLP-1RAs: Glucagon-like peptide-1 receptor agonists HR: Hazard ratio References Abdul Basith Khan M, Hashim MJ, King JK, Govender RD, Mustafa H, Al Kaabi J

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Seek immediate medical attention for persistent right upper quadrant pain lasting more than 6 hours, fever above 100.4F, jaundice (yellowing of skin or eyes), severe vomiting, or signs of infection

Such range allows flexibility