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Considering the reduced biosynthetic capacity of erythrocytes, they accumulate oxidative changes along their life span and, therefore, the OS-induced changes in RBCs could be used as useful biomarkers in several pathological and physiological conditions

Summary of various factors affecting tamoxifen resistance is summarized in Fig

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In view of the findings, the precise role of oxidative stress in the pathogenesis of hypertension in SHR needs to be investigated further, in particular the significance of the altered CAT and GPx activities

This typically includes a four-point salivary cortisol curve, thyroid panel (TSH, Free T3, Free T4, Reverse T3, thyroid antibodies), sex hormone assessment, and DHEA-S