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Moreover, the matrine-derived compound MASM, which has anticancer and anti-inflammatory effects, has been shown to suppress the transformation of astrocytes into the toxic form, offering benefits in conditions such as autoimmune encephalomyelitis and multiple sclerosis 153

Unlike classic probiotics, mainly from Lactobacillus and Bifidobacterium genera, NGPs are usually chosen from groups such as Bacteroides, Akkermansia , Faecalibacterium , Eubacterium , and related butyrate- or propionate-producing species (532, 538)

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