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Ongoing medical supervision is recommended and critical to avoid adverse side effects

This approach uses lower doses, up to 1.5 mg twice weekly injections

This objective data helps clinicians distinguish between true polyuria (excessive urine production) and urinary frequency with normal total volume, guiding appropriate investigation

These include: Patients currently taking another GLP-1 medication cannot take semaglutide at the same time, though they may be able to switch under provider supervision

First, administration is once weekly, not daily semaglutides long half-life is the whole reason the label uses a weekly cadence