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Physiological levels of ROS are also required for the acrosome reaction, which is the process by which sperm release enzymes that allow them to penetrate the zona pellucida, the protective layer surrounding the oocyte (45, 46)

Nuamnaichati N, Mangmool S, Chattipakorn N, Parichatikanond W (2020) Stimulation of GLP-1 receptor inhibits methylglyoxal-induced mitochondrial dysfunctions in H9c2 cardiomyoblasts: potential role of Epac/PI3K/Akt pathway

Broad Institute / Gene Expression Omnibus Lee et al

To evaluate the effect of the intervention on levels of B vitamins and taurine, blood markers were included as exploratory outcomes

Altogether, these data suggest that the upregulation of GSH, rather than the dTTP pool, is responsible for avoiding oncogene-induced replication stress and less susceptibility to JMF4073 in T315I-Bcr-Abl-32D cells