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While that's substantially higher than the 600mg starting dose we generally favor for people new to NAC, it reflects the GlyNAC protocols studied in healthy-aging research.34 57 58 Some readers may prefer to start with a smaller serving for tolerability, but the clinical research on GlyNAC has generally evaluated gram-level doses of both ingredients, so it's unclear whether substantially lower amounts would provide the same benefits

doi:10.1046/j.0022-202x.2001.01469.x

doi:10.1016/j.tips.2013.01.001

Figure 1: Changes in A) escape latency and B) time spent in quadrants across all treatment groups

Likewise, always check the expiry date