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The onset of reactions varied, occurring between 4 weeks and 3 years after medication initiation
Overexpression of gastric leptin precedes adipocyte leptin during high-fat diet and is linked to 5HT-containing enterochromaffin cells
We classified the available evidence into four categories: (1) basic and translational research, (2) observational clinical studies, (3) RCTs and associated meta-analysis, and (4) pharmacovigilance studies
Clinical trials are done before a medication is approved by the FDA
These patients reduced their initial weight by 5% through a low-calorie diet during the 4-12 weeks pre-trial induction period
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