Neuroleptic malignant syndrome, with symptoms such as muscle stiffness, high fever, unstable blood pressure, and confusion, requires stopping the medication immediately and close monitoring
It is possible that dehydroascorbylation could act as a specific regulatory post-translational protein modification responding to increased ascorbate oxidation rather than as generic damage, but so far there is no evidence for this role
Many patients initially prefer oral medications due to familiarity and convenience
Individuals that have overdosed on paracetamol, in general, have no specific symptoms for the first 24 hours
The colonies were inoculated into 200 L YP20D medium containing 14 mM of acrolein, and cultivated at 30 C and 900 rpm for 48 h