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Beyond this drug class, NICE guideline NG28 for type 2 diabetes management recommends various alternatives including: SGLT2 inhibitors such as dapagliflozin or empagliflozin, which offer cardiovascular and renal protective benefits DPP-4 inhibitors like sitagliptin, which have a favourable side effect profile Traditional agents including metformin, sulphonylureas, or insulin therapy, depending on disease progression and individual circumstances When preparing to discuss concerns about Ozempic with your GP, it is helpful to document specific symptoms, their timing in relation to doses, their impact on daily activities, and any measures already attempted to manage them

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Based on basic NMA assumptions, only outcomes including those of head-to-head comparison studies were estimated as multiple treatment comparisons