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Authors are thankful to Indian Council of Medical Research (ICMR), New Delhi, (F.No: 59/07/2020/TRM/BMS;Dated:25032021)

AH-8 inhibits acetylcholine release at the neuromuscular junction

Binding of ACE to PCBP1/2 induces ferroptosis To investigate whether ACE directly binds to PCBP1 and PCBP2, we used a cellular thermal shift assay (CETSA) to detect whether the thermal stability of the proteins changed after ACE treatment

To reconvert DHA into AscH , DHAR uses reduced glutathione (GSH), which is then oxidized to glutathione disulfide (GSSG)

The clinical and nonclinical safety record was subsequently marshaled in support of a Generally Recognized as Safe (GRAS) determination for AOD9604 as a dietary ingredient, conditional on publication of the underlying safety data [7]