Similarly, naringin was reported to alleviate OS and enhance the activity of endogenous antioxidants in streptozotocin-induced DN models, thereby improving behavioral, biochemical, and OS parameters, reducing TNF-/IL-6, and restoring brain/pancreatic tissue integrity ( 4.2 Scavenging of ROS Natural antioxidants, such as polyphenols, flavonoids, and carotenoids, can directly scavenge free radicals and reactive oxygen species, thereby neutralizing their harmful effects
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- Glutathione and reduction of neuropathy from platin chemotherapy drugs
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