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Keywords: aesthetic, oxidative stress, preventive, curative, aging, hair graying Introduction Hair graying is a prominent sign of aging, commonly attributed to a decrease in follicular melanocyte stem cells (MSCs) or their dysfunction, affecting melanin production and transforming hair into gray

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Emerging evidence suggests that glucose metabolic regulation plays a pivotal role in modulating the TME by alleviating extracellular acidification and improving immune cell function, thereby overcoming immune tolerance and enhancing the therapeutic outcomes of immunotherapy [132]