235,360,361 Another hypothesis is that hepatocytes undergo a transient epithelialmesenchymal transition to escape the suppressive effects of elevated TGF- levels
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It can be counteracted on a cellular level by the Nrf2 pathway, which is necessary for upregulating genes that combat reactive oxygen species.[ref] Zearalenone: Glucuronidation is a phase II detoxification process by which a glucuronic acid molecule is added to a toxin to make it more easily excreted and less reactive
Because the micronutrient deficiencies will occur in those cells, which accumulate aldehydes, localized intracellular deficiencies are not likely to be amenable to detection by erythrocyte and urine clinical assays that only measure the average nutritional status
Identification of type I iodothyronine 5-deiodinase as a selenoenzyme
