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It works by reducing the amount of sugar your liver releases into your blood, and making your cells respond better to insulin, so they take up more sugar from the blood

Fedoreyeva, L

This can help reduce the amount of food you eat, which is why semaglutide is also used for weight loss

Notably, increased NAD+ levels also activate NAD+dependent signaling pathways such as sirtuins (SIRT1/SIRT3), further enhancing mitochondrial biogenesis and energy metabolism