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It has been established that astrocytes are key to CNS metabolism of GSH, but further research is also required to explore the correlation between GSH levels in astrocytes and overall GSH content in the brain (Dringen and Arend, 2025)
The glutathione reductase enzyme turns oxidized GSSG back into active GSH
It is a known antioxidant and detoxifies xenobiotics (chemical substances foreign to living beings)
[DOI] [PubMed] [Google Scholar] 179.Ehlhardt W.J., Woodland J.M., Worzalla J.F., Bewley J.R., Grindey G.B., Todd G.C., Toth J.E., Howbert J.J