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Compounded formulations vary in concentration, potency, and additives

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In addition to their contributions in controlling blood glucose levels, a number of pleiotropic effects have been described for this class of compounds, including the glucose-independent reduction of glomerular hyperfiltration and albuminuria 10,11 and the protective effects in the diabetic kidney disease

However, certain studies have failed to establish a preventive effect of SGLT2 inhibitors on prostate cancer [102]