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97 In a model of lipopolysaccharide (LPS)-induced inflammation, liraglutide inhibited the polarization of pro-inflammatory microglia and promoted the polarization of anti-inflammatory microglia, diminished inflammatory cytokine expression, and decreased NF-B pathway activation
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Side Effects Bleeding: most common and serious risk (nosebleeds, gum bleeding, bruising, gastrointestinal bleeding) Skin necrosis: rare, usually early in therapy Purple toe syndrome: rare complication Teratogenic: dangerous in pregnancy (especially first trimester) Interactions Drugs: Many antibiotics, antifungals, and NSAIDs can increase bleeding risk or alter INR
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