Tesamorelin occupies the GHRH lane
Ipamorelin is a synthetic pentapeptide, Aib-His-D-2-Nal-D-Phe-Lys-NH2, described in peer-reviewed research as a selective growth-hormone secretagogue acting through the ghrelin/growth-hormone-secretagogue receptor system
None of these peptides are licensed medicines in the UK
What This Means for Peptide Therapy Patients Peptide compounds like Sermorelin or CJC-1295/Ipamorelin are increasingly used for: Anti-aging protocols Post-injury recovery Energy, sleep, and muscle support But without understanding IGFBP-3, these therapies may: Look falsely effective (if IGF-1 rises but free IGF-1 is excessive) Pose hidden risks (if protective binding is insufficient) We use IGF-1 : IGFBP-3 ratio analysis as a tool for: Refining dosage Adjusting protocols Monitoring cancer risk Supporting safe, individualized regenerative therapies Functional Testing in a Root-Cause Framework At Internal Healing & Wellness MD, we use advanced lab testing to interpret growth hormone signaling, assess whole-body function, and guide individualized protocols
For example: Two human trials one in 2006, the other in 2013 found that even very small weekly doses (30-90mcg) of CJC-1295 resulted in increased [minimum] and mean [growth hormone] secretion and
