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Gastrointestinal Adverse Events Gastrointestinal (GI) adverse events are the hallmark safety finding with all GLP-1 receptor agonists, reflecting the physiological effects of GLP-1 signaling on gastric motility, gastric emptying, and central appetite regulation

Novo Nordisk already sells a similar once-a-day shot, Victoza

Follow-up studies and disease registries will be essential to determine whether such benefits translate into lower CKD progression rates or cancer incidence in MASH cohorts

While effective for immediate symptom resolution, this approach shuts down endogenous production by triggering a negative feedback loop