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RSL3 inhibits mTOR signaling in thyroid cancer cells The mTOR signaling pathway has recently been implicated in counteracting ferroptosis by regulating ROS production 20 , therefore, it was important to examine the effects of RSL3 on mTOR signaling pathway and its downstream proteins and whether inactivation of mTOR pathway signaling will occur in thyroid cancer cells with GPX4 inhibition

It is also worth understanding the context in which this and similar small studies were conducted

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However, the data tell a more nuanced story