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The methanol extract of MC inhibits the expression of inducible nitric oxide synthase (iNOS) and Cyclooxygenase (COX)-2 by inhibiting the phosphorylation of Inhibitor-B (I-B) by LPS and the activation of NF-B in macrophages, leading to decrease in the concentrations of TNF-, IL-1 and IL-6, which confirms its anti-inflammatory effect (97)

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These signals are normal and reflect healthy appetite regulation

GLP-1 receptor activation in the amygdala, the brains fear center, appears to dampen anxiety-related responses