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But what makes it especially interesting for skincare is its potential to influence melanin production

This is the reason many clinicians historically preferred indirect strategies such as supplying precursors like N-acetylcysteine or using intravenous glutathione in hospital settings

NNMT is expressed in some cancer cells, which makes interpretation of inhibition complex: effects could differ by cancer type or stage, and the data are largely from models rather than long-term human study

It helps to keep the integrity of myelin sheath on nerves by converting homocysteine to methionine