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Patients usually vomit until the stomach ejects all of its food content

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These findings suggest a relationship between decreased M3 mAChR protein expression and the cholinergic response recovered upon metformin treatment in pancreatic islets isolated from MSG-rats

Since IR and compensatory hyperinsulinemia have been considered frequently occurring features of the syndrome, it is now widely recognized that, in addressing and treating the various clinical aspects of PCOS, IR is a problem that needs to be evaluated and solved (4)