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There is considerable evidence that strategies designed to lower postprandial glycaemia in type 2 diabetes by boosting GLP-1 secretion are preferably delivered before a meal [20,21,22]

[52] Rollet M, Bohn T, Vahid F, On Behalf Of The Oriscav Working Group

Semaglutide and other GLP1R agonists have transformed the treatment landscape for obesity and type 2 diabetes, primarily through their appetite-suppressing and weight-reducing actions

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The FDA confirmed in February 2025 that compounded semaglutide remains legal through 503A pharmacies for patients with documented medical need (allergy, non-commercial strength, or different delivery route), but warned 30 telehealth companies against illegal marketing of compounded GLP-1s [3]