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Testing b12 after 6 to 12 months of semaglutide use makes more sense than presumptive supplementation

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Primary risks include additive cardiovascular effects (increased heart rate and blood pressure), intensified gastrointestinal symptoms (nausea, vomiting, diarrhea), and potential for serious adverse events including pancreatitis and acute kidney injury requiring close monitoring

Importance of Medical Supervision: Regular monitoring by a healthcare professional is crucial for managing potential side effects and optimizing treatment