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genetic variants can cause body odor that may respond to riboflavin ETFDH transfers electrons in the mitochondrial energy production pathway

ABOUT THE GUEST: Flynn Mcguire, MD is a physical medicine and rehabilitation resident at the University of Utah

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Using this in vitro ubiquitination assay together with the purified catalytically inactive C4516A mutant of RNF213(371-5207), which loses the E3 enzymatic activity of its RZF domain and cannot undergo auto-ubiquitination 50 , we revealed that IpaH1.4 can directly catalyze the ubiquitination of RNF213 in vitro (Fig