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A spokesperson said: "NAION is not listed as a known adverse drug reaction" for marketed formulations of semaglutude - Ozempic, Rybelsus and Wegovy

01Mechanism of action ERR receptors Orphan nuclear receptor family Estrogen-Related Receptors (ERRalpha, beta, gamma) were isolated in 1988 by Vincent Giguere (Nature 331:91) based on strong sequence homology with the estrogen receptor alpha (ESR1) in their DNA-binding (DBD, 68% identity) and ligand-binding (LBD, 36% identity) domains

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Several pharmaceutical manufacturers are working to develop pill-based alternatives to injectable treatments