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Among these, nanoparticles (20 - 200 nm) stand out for their enhanced solubility and targeted delivery capabilities, though they face challenges such as potential toxicity and clearance by the mononuclear phagocyte system (MPS) (7)

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With the beneficial effect of BPC 157 therapy, this can occur along with blocking VEGF signaling during the angiogenic switch and initial tumor growth [95] and the counteraction of severe adverse effects occurring with cytostatic drug applications [180,181,182], thereby improving their anti-tumor effectiveness