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In those, loss of NRF2 resulted in a more rapid onset and more severe clinical course of the EAE model, which was accompanied by increased glial activation, exacerbated spinal cord damage, and axonal degeneration as well as increased levels of proinflammatory cytokines (Rehman et al., 2019)

FIGURE 1 ATP Acts Both Within and Beyond the Red Blood Cell to Modulate Blood (Red Blood Cell) Flow The determinants of RBC deformability are numerous and complex

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