retatrutide cons Comparing the Big 3, Semaglutide, Tirzepatide and : r/Mounjaro Retatrutide vs Mounjaro: triple agonist

GLP-1 RA: glucagon-like peptide-1 receptor agonist

GLP-1 is degraded rapidly by the ubiquitous enzyme dipeptidyl-peptidase IV (DPP-4)

Additionally, NAD+ contributes to the regulation of genes associated with aging

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Mainville et al 15 described a 59-year-old woman with refractory HS who showed improvement with a combination of intravenous ertapenem 1 g/d for 6 weeks, minocycline 100 mg/d for 3 months, metformin 500 mg three times daily for 2 months, doxycycline 100 mg/d to bridge to adalimumab (160 mg subcutaneously starting dose then 80 mg subcutaneously), and semaglutide (no dosage listed)