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39 Most studies used B12 i.m., with slightly varying dosing regimens, commonly 1000 g daily for 57 days, followed by weekly injections for another 34 weeks, and then monthly injections

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One small human study found that 7 out of 12 patients with chronic knee pain reported meaningful relief lasting six months or more after a single injection

Among the GLP-1 RAs, evidence of CV benefit is strongest for liraglutide, favorable for semaglutide, and less certain for exenatide

Mild Nausea or Diarrhea: Less common, but can occur