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Discontinuation rates due to adverse events were reported as low and single-digit across both REDEFINE 1 and 2, which Novo Nordisk highlighted as a positive tolerability signal given the drugs dual-mechanism approach

References Park JT, Strominger JL

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Change history 18 September 2025 Following the article's publication, the Funding section was updated

[PubMed] Brzoska T, Luger TA, Maaser C, Abels C, Bhm M