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One potential concern is the dose

Less common but more serious: pancreatitis (rare but documented), gallbladder issues including gallstones, and potential thyroid concerns based on animal data

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That said, severe symptoms like chest pain, confusion, uncontrollable vomiting, or signs of stroke or heart attack require emergency care

Saylor et al., 2016), rather than T-cells, which largely drive peripheral pathogenesis (Deeks et al., 2015)