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Each round consisted of 3 days of DMSA/placebo (as in Phase 1), followed by 11 days of no DMSA/placebo

This article does not provide preparation or dosing instructions

Loss of GSH synthesis induces transcription of NRF2 target genes and repression of lipogenic genes GSH synthesis is required for numerous enzymatic processes across a range of cell types in the body

[1] In cultured mouse adipocytes, exposure to a methylquinolinium NNMT inhibitor raised intracellular NAD+ and SAM and lowered lipogenesis