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Number of animals per group and timepoint: For the 300 mg/kg APAP cohort, control and LKO mice were analyzed at 0 h ( n = 4 control, 5 LKO), 6 h ( n = 4 control, 6 LKO), 12 h ( n = 6 control, 4 LKO), 24 h ( n = 7 control, 5 LKO), 48 h ( n = 4 control, 4 LKO), 72 h ( n = 4 control, 4 LKO), and 96 h ( n = 3 control, 4 LKO)

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Mutations in the histamine N-methyltransferase gene, HNMT, are associated with nonsyndromic autosomal recessive intellectual disability

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Step 3: Pour into the mold Pour the soap into your mold and set aside to cool