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The sauna is causing vasodilation and the cold plunge or cold exposure is causing vasoconstriction

In addition, two free -carboxyl groups of exogenous GSH can protonate with increasing acidity in the extracellular environment (e.g., culture media), which may also be associated with antibacterial activity

Autophagy can participate in the redox balance by clearing oxidative stress-damaged molecules and organelles (Yun et al., 2020)