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Scientists have done several studies on this topic

Atrial remodeling and atrial fibrillation: mechanisms and implications

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Agarwal R, Georgianos PI

For instance, both semaglutide and some antidepressants (particularly SSRIs or SNRIs) can cause gastrointestinal issues such as nausea or diarrhea, which may intensify when taken together. GLP-1s and depression Experts continue to explore the potential effect that taking a medication like semaglutide could have on your mental health