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Finally, a phase II study is currently underway investigating whether fecal microbiota transplantation can reverse HE in cirrhotic patients with episodic HE despite maintenance therapy with lactulose and/or rifaximin

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In vivo, it is not actually going to bind to albumin, but [the glycan] has sialic acid moieties, which also reduces the liver metabolism, and thus increases the circulating half-life in the blood, explains Melbourne researcher Chaitra Chandrashekar, who carried out the work

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