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Chisalita SI, Johansson GS, Liefvendahl E, Back K, Arnqvist HJ: Human aortic smooth muscle cells are insulin resistant at the receptor level but sensitive to IGF1 and IGF2

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It is generally believed that most cortical cataracts are osmotic in naturethat is, water accumulates in, or between, the lens cells usually as a result of ionic imbalances

For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA)

It is a analog of human IGF-1 comprising the complete human IGF-1 sequence with the substitution of an Arginine (Arg or R) for the Glutamic Acid (Glu or E) at position 3 (hence R3), and a 13 amino acid extension peptide at the N-terminus