A second research literature concerns the microbial metabolism of dietary carnitine rather than carnitine itself: Koeth and colleagues (Nat Med, 2013) reported that gut microbiota convert carnitine to trimethylamine, which is oxidised hepatically to trimethylamine-N-oxide, and examined the association of that metabolite with atherosclerosis in animal models
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Furthermore, the metabolic state-driven approach has been successfully adopted in combating antibiotic-resistant pathogens that are seriously harmful to humans
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