Insulin, a hormone produced by the pancreas -cells, regulates glucose metabolism
Despite these changes, food intake, energy expenditure, respiratory quotient, ambulatory activity and leptin sensitivity were not affected in these mice (Supplementary Fig
on 24 patients with generalized vitiligo and 20 healthy controls found statistically significant higher levels of superoxide dismutase activity in erythrocytes, serum MDA, and nitric oxide (NO) and statistically significant lower levels of glutathione and glutathione peroxidase in the patients of vitiligo compared to the controls.[] Secondary to the oxidative stress, the polyunsaturated fatty acids undergo peroxidation resulting in formation of free radicals
GSH effectively scavenges free radicals and other ROS and RNS (e.g., hydroxyl radical, lipid peroxyl radical, superoxide anion, and hydrogen peroxide) directly and indirectly through enzymatic reactions
Huang, V