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Research is ongoing, but one study of patients with T2D, published in early 2024, indicated that GLP-1s did not increase the risk of major congenital malformations compared to those taking insulin

Those without such a diagnosis often face denied claims

As the number of people using these diabetes weight loss drugs continues to grow, drugmakers continue to earn more and more profit from what they are manufacturing and selling

These effects contribute to weight loss that varies by agent and dosetypically ranging from 5-8% with liraglutide 3 mg (Saxenda), up to 15% with semaglutide 2.4 mg (Wegovy), and potentially up to 20% with higher doses of tirzepatide (Zepbound)

What Retatrutide Is Retatrutide represents the forefront of weight-loss pharmacology, operating as a triple-agonist