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Risk factors include genetics, repetitive strain, obesity, smoking, diabetes, and a sedentary lifestyle.Why It Happens Causes (Etiology and Pathophysiology)The main cause of degenerative disc disease is loss of hydration in the discs, which makes them less resilient

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For example, in our evaluation of postmortem human brain tissue from individuals with various levels of AD neuropathology, we observed a wide range (0-15%) of senescent cell burden (39)

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